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Circ‐SPECC1 modulates TGFβ2 and autophagy under oxidative stress by sponging miR‐33a to promote hepatocellular carcinoma tumorigenesis

Circular RNAs (circRNAs) play vital roles in the pathogenesis and development of multiple cancers, including hepatocellular carcinoma (HCC). Nevertheless, the regulatory mechanisms of circ‐SPECC1 in HCC remain poorly understood. In our study, we found that circ‐SPECC1 was apparently downregulated in...

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Sonraí Bibleagrafaíochta
Foilsithe in:Cancer Med
Main Authors: Zhang, Bin, Liu, Zhiyi, Cao, Kuan, Shan, Wengang, Liu, Jin, Wen, Quan, Wang, Renhao
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433841/
https://ncbi.nlm.nih.gov/pubmed/32627938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3219
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