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Neural compensation in presymptomatic hAPP mouse models of Alzheimer's disease

Largely inspired from clinical concepts like brain reserve, cognitive reserve, and neural compensation, here we review data showing how neural circuits reorganize in presymptomatic and early symptomatic hAPP mice to maintain memory intact. By informing on molecular alterations and compensatory adapt...

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Bibliographic Details
Published in:Learn Mem
Main Author: Ammassari-Teule, Martine
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433654/
https://ncbi.nlm.nih.gov/pubmed/32817305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.050401.119
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