Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions

BACKGROUND: African Americans (AA) are at high risk for Colorectal Cancer (CRC). Studies report a 30–60% increase in CRC risk with physical inactivity, obesity and metabolic syndrome. Activation of the WNT/β-catenin (CTNNB1) signaling pathway plays a critical role in colorectal carcinogenesis. Accum...

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Vydáno v:BMC Gastroenterol
Hlavní autoři: Shokrani, Babak, Brim, Hassan, Hydari, Tahmineh, Afsari, Ali, Lee, Edward, Nouraie, Mehdi, Sherif, Zaki, Ashktorab, Hassan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433356/
https://ncbi.nlm.nih.gov/pubmed/32811441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-020-01412-x
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