Anxiety and Startle Phenotypes in Glrb Spastic and Glra1 Spasmodic Mouse Mutants

A GWAS study recently demonstrated single nucleotide polymorphisms (SNPs) in the human GLRB gene of individuals with a prevalence for agoraphobia. GLRB encodes the glycine receptor (GlyRs) β subunit. The identified SNPs are localized within the gene flanking regions (3′ and 5′ UTRs) and intronic reg...

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Pubblicato in:Front Mol Neurosci
Autori principali: Schaefer, Natascha, Signoret-Genest, Jérémy, von Collenberg, Cora R., Wachter, Britta, Deckert, Jürgen, Tovote, Philip, Blum, Robert, Villmann, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433344/
https://ncbi.nlm.nih.gov/pubmed/32848605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00152
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