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Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes

BACKGROUND: Undercarboxylated osteocalcin (ucOC) is a secreted protein produced by osteoblasts that regulates insulin secretion and insulin sensitivity in rodents. However, the significance of these effects on glucose metabolism in human remains unknown. Moreover, the pathophysiological roles of ucO...

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Bibliografiske detaljer
Udgivet i:Diabetol Metab Syndr
Main Authors: Funakoshi, Shogo, Yoshimura, Kumiko, Hirano, Seiki, Ohmi, Satoko, Amano, Eri, Fukuda, Yoshiharu, Terada, Yoshio, Fujimoto, Shimpei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433182/
https://ncbi.nlm.nih.gov/pubmed/32821293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-020-00579-3
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