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Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B

BACKGROUND: Partial or an entire deletion of SHANK3 are considered as major drivers in the Phelan–McDermid syndrome, in which 75% of patients are diagnosed with autism spectrum disorder (ASD). During the recent years, there was an increasing interest in stem cell therapy in ASD, and specifically, me...

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Vydáno v:Mol Autism
Hlavní autoři: Perets, N., Oron, O., Herman, S., Elliott, E., Offen, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433169/
https://ncbi.nlm.nih.gov/pubmed/32807217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00366-x
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