Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma

BACKGROUND: SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitrosamine (DEN)-induced HCC. As SOCS1 and SOCS3 are important...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Khan, Md Gulam Musawwir, Ghosh, Amit, Variya, Bhavesh, Santharam, Madanraj Appiya, Ihsan, Awais Ullah, Ramanathan, Sheela, Ilangumaran, Subburaj
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433106/
https://ncbi.nlm.nih.gov/pubmed/32807134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07285-3
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