Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma

BACKGROUND: SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitrosamine (DEN)-induced HCC. As SOCS1 and SOCS3 are important...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Khan, Md Gulam Musawwir, Ghosh, Amit, Variya, Bhavesh, Santharam, Madanraj Appiya, Ihsan, Awais Ullah, Ramanathan, Sheela, Ilangumaran, Subburaj
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433106/
https://ncbi.nlm.nih.gov/pubmed/32807134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07285-3
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