Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma

BACKGROUND: SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitrosamine (DEN)-induced HCC. As SOCS1 and SOCS3 are important...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Khan, Md Gulam Musawwir, Ghosh, Amit, Variya, Bhavesh, Santharam, Madanraj Appiya, Ihsan, Awais Ullah, Ramanathan, Sheela, Ilangumaran, Subburaj
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433106/
https://ncbi.nlm.nih.gov/pubmed/32807134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07285-3
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