Melanoma risk for CDKN2A mutation carriers who are relatives of population-based case carriers in Australia and the United Kingdom

BACKGROUND: CDKN2A mutations confer a substantial risk of cutaneous melanoma, however the magnitude of the risk is uncertain. METHODS: We estimated the hazard ratio (HR) and the average age-specific cumulative risk (i.e. penetrance) of reported melanoma for CDKN2A mutation carriers in case families...

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Bibliografiska uppgifter
I publikationen:J Med Genet
Huvudupphovsmän: Cust, Anne E, Harland, Mark, Makalic, Enes, Schmidt, Daniel, Dowty, James G, Aitken, Joanne F, Agha-Hamilton, Chantelle, Armstrong, Bruce K, Barrett, Jenny H, Chan, May, Chang, Yu-Mei, Gascoyne, Joanne, Giles, Graham G, Holland, Elizabeth A, Kefford, Richard F, Kukalizch, Kairen, Lowery, Johanna, Randerson-Moor, Juliette A, Schmid, Helen, Taylor, Claire F, Whitaker, Linda, Hopper, John L, Newton-Bishop, Julia A, Mann, Graham J, Bishop, D Timothy, Jenkins, Mark A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432952/
https://ncbi.nlm.nih.gov/pubmed/21325014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2010.086538
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