Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure

Gut microbiota-dependent metabolites, in particular trimethylamine (TMA), are linked to hypertension. Maternal 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure or consumption of food high in fructose (HFR) can induce hypertension in adult offspring. We examined whether 3,3-maternal dimethyl-1-but...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Hsu, Chien-Ning, Chan, Julie Y. H., Yu, Hong-Ren, Lee, Wei-Chia, Wu, Kay L. H., Chang-Chien, Guo-Ping, Lin, Sufan, Hou, Chih-Yao, Tain, You-Lin
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432895/
https://ncbi.nlm.nih.gov/pubmed/32752013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21155488
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