Orally Administered Exosomes Suppress Mouse Delayed-Type Hypersensitivity by Delivering miRNA-150 to Antigen-Primed Macrophage APC Targeted by Exosome-Surface Anti-Peptide Antibody Light Chains

We previously discovered suppressor T cell-derived, antigen (Ag)-specific exosomes inhibiting mouse hapten-induced contact sensitivity effector T cells by targeting antigen-presenting cells (APCs). These suppressive exosomes acted Ag-specifically due to a coating of antibody free light chains (FLC)...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Nazimek, Katarzyna, Bryniarski, Krzysztof, Ptak, Wlodzimierz, Groot Kormelink, Tom, Askenase, Philip W.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432818/
https://ncbi.nlm.nih.gov/pubmed/32748889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21155540
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