PD-L1 Expression and a High Tumor Infiltrate of CD8+ Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma

Carcinogenesis of human papillomavirus (HPV)-related (+) oropharyngeal squamous cell carcinoma (OPSCC) differs from HPV-negative (–) OPSCC. HPV-related immune-escape-mechanism could be responsible for the development and progression of HPV+ tumors and an immunophenotype different from HPV– OPSCC is...

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Publicado en:Int J Mol Sci
Autores principales: Wuerdemann, Nora, Gültekin, Sibel E., Pütz, Katharina, Wittekindt, Claus, Huebbers, Christian U., Sharma, Shachi J., Eckel, Hans, Schubotz, Anna B., Gattenlöhner, Stefan, Büttner, Reinhard, Speel, Ernst-Jan, Klussmann, Jens P., Wagner, Steffen, Quaas, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432501/
https://ncbi.nlm.nih.gov/pubmed/32718057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21155228
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