Production of dengue virus-like particles serotype-3 in silkworm larvae and their ability to elicit a humoral immune response in mice

To develop monovalent dengue virus-like particle for serotype 3 (DENV-LP/3), we prepared and expressed two structural polyprotein constructs using silkworm and Bm5 cells: DENV-3 Capsid-premembrane-envelope (DENV-3CprME) and premembrane-envelope (DENV-3prME). The expressed PA-tagged 3CprME and 3prME...

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Dettagli Bibliografici
Pubblicato in:AMB Express
Autori principali: Utomo, Doddy Irawan Setyo, Pambudi, Sabar, Sjatha, Fithriyah, Kato, Tatsuya, Park, Enoch Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431508/
https://ncbi.nlm.nih.gov/pubmed/32804287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01087-3
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