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OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation

Glioblastoma contains a rare population of self-renewing brain tumor stem cells (BTSCs) which are endowed with properties to proliferate, spur the growth of new tumors, and at the same time, evade ionizing radiation (IR) and chemotherapy. However, the drivers of BTSC resistance to therapy remain unk...

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Опубликовано в: :Nat Commun
Главные авторы: Sharanek, Ahmad, Burban, Audrey, Laaper, Matthew, Heckel, Emilie, Joyal, Jean-Sebastien, Soleimani, Vahab D., Jahani-Asl, Arezu
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431428/
https://ncbi.nlm.nih.gov/pubmed/32807793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17885-z
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