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The unusual structure of Ruminococcin C1 antimicrobial peptide confers clinical properties

The emergence of superbugs developing resistance to antibiotics and the resurgence of microbial infections have led scientists to start an antimicrobial arms race. In this context, we have previously identified an active RiPP, the Ruminococcin C1, naturally produced by Ruminococcus gnavus E1, a symb...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Roblin, Clarisse, Chiumento, Steve, Bornet, Olivier, Nouailler, Matthieu, Müller, Christina S., Jeannot, Katy, Basset, Christian, Kieffer-Jaquinod, Sylvie, Couté, Yohann, Torelli, Stéphane, Le Pape, Laurent, Schünemann, Volker, Olleik, Hamza, De La Villeon, Bruno, Sockeel, Philippe, Di Pasquale, Eric, Nicoletti, Cendrine, Vidal, Nicolas, Poljak, Leonora, Iranzo, Olga, Giardina, Thierry, Fons, Michel, Devillard, Estelle, Polard, Patrice, Maresca, Marc, Perrier, Josette, Atta, Mohamed, Guerlesquin, Françoise, Lafond, Mickael, Duarte, Victor
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431081/
https://ncbi.nlm.nih.gov/pubmed/32719135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004045117
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