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Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells

A better understanding of how antibiotic exposure impacts the evolution of resistance in bacterial populations is crucial for designing more sustainable treatment strategies. The conventional approach to this question is to measure the range of concentrations over which resistant strain(s) are selec...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Alexander, Helen K., MacLean, R. Craig
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431077/
https://ncbi.nlm.nih.gov/pubmed/32703812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919672117
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