Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Around the tenth day after diagnosis, ∼20% of patients with coronavirus disease 2019 (COVID-19)−associated pneumonia evolve toward severe oxygen dependence (stage 2b) and acute respiratory distress syndrome (stage 3) associated with systemic inflammation often termed a “cytokine storm.” Because inte...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Cauchois, Raphaël, Koubi, Marie, Delarbre, David, Manet, Cécile, Carvelli, Julien, Blasco, Valery Benjamin, Jean, Rodolphe, Fouche, Louis, Bornet, Charleric, Pauly, Vanessa, Mazodier, Karin, Pestre, Vincent, Jarrot, Pierre-André, Dinarello, Charles A., Kaplanski, Gilles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430998/
https://ncbi.nlm.nih.gov/pubmed/32699149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009017117
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