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Model-Informed Development of Sotalol Loading and Dose Escalation Employing an Intravenous Infusion
BACKGROUND: Sotalol is often employed to prevent recurrence of symptomatic atrial flutter/atrial fibrillation. Because sotalol can prolong the QT interval excessively causing ventricular arrhythmias, a 3-day in-hospital loading or dose escalation period is mandated with oral administration in the pr...
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| Publicat a: | Cardiol Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elmer Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7430892/ https://ncbi.nlm.nih.gov/pubmed/32849964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14740/cr1143 |
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