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A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

Human coronavirus NL63 (HCoV-NL63) is an enveloped pathogen of the family Coronaviridae that spreads worldwide and causes up to 10% of all annual respiratory diseases. HCoV-NL63 is typically associated with mild upper respiratory symptoms in children, elderly and immunocompromised individuals. It ha...

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Podrobná bibliografie
Vydáno v:bioRxiv
Hlavní autoři: Zhang, Kaiming, Li, Shanshan, Pintilie, Grigore, Chmielewski, David, Schmid, Michael F., Simmons, Graham, Jin, Jing, Chiu, Wah
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430573/
https://ncbi.nlm.nih.gov/pubmed/32817943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.11.245696
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