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Ambroxol and Ciprofloxacin Show Activity Against SARS-CoV2 in Vero E6 Cells at Clinically-Relevant Concentrations

We studied the activity of a range of weakly basic and moderately lipophilic drugs against SARS CoV2 in Vero E6 cells, using Vero E6 survival, qPCR of viral genome and plaque forming assays. No clear relationship between their weakly basic and hydrophobic nature upon their activity was observed. How...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Bradfute, Steven B, Ye, Chunyan, Clarke, Elizabeth C, Kumar, Suresh, Timmins, Graham S, Deretic, Vojo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430564/
https://ncbi.nlm.nih.gov/pubmed/32817934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.11.245100
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