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Hydroxychloroquine: mechanism of action inhibiting SARS-CoV2 entry.

Hydroxychloroquine (HCQ) has been proposed in the treatment of SARS-coronavirus 2 (SARS-CoV-2) infection, albeit with much controversy. In vitro, HCQ effectively inhibits viral entry, but its use in the clinic has been hampered by conflicting results. A better understanding of HCQ’s mechanism of act...

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Detalles Bibliográficos
Publicado en:bioRxiv
Main Authors: Yuan, Zixuan, Pavel, Mahmud Arif, Wang, Hao, Hansen, Scott B.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430563/
https://ncbi.nlm.nih.gov/pubmed/32817933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.13.250217
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