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Single cell distribution analysis of AR levels by high throughput microscopy in cell models: application for testing endocrine disrupting chemicals

Cell-to-cell variation of protein expression in genetically homogeneous populations is a common biological trait often neglected during analysis of high throughput (HT) screens, and is rarely used as a metric to characterize chemicals. We have captured single cell distributions of androgen receptor...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Stossi, Fabio, Mistry, Ragini M., Singh, Pankaj K., Johnson, Hannah L., Mancini, Maureen G., Szafran, Adam T., Mancini, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430197/
https://ncbi.nlm.nih.gov/pubmed/32552291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220934420
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