Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

PURPOSE: One of the main challenges in cancer therapy is the identification of molecular mechanisms mediating resistance or sensitivity to treatment. Cytidine deaminase (CDA) was reported to be downregulated in cells derived from patients with Bloom syndrome, a genetic disease associated with a stro...

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Pubblicato in:Clin Cancer Res
Autori principali: Mameri, Hamza, Bièche, Ivan, Meseure, Didier, Marangoni, Elisabetta, Buhagiar-Labarchéde, Géraldine, Nicolas, André, Vacher, Sophie, Onclercq-Delic, Rosine, Rajapakse, Vinodh, Varma, Sudhir, Reinhold, William C., Pommier, Yves, Amor-Guéret, Mounira
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430158/
https://ncbi.nlm.nih.gov/pubmed/27601591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0626
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