Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

PURPOSE: One of the main challenges in cancer therapy is the identification of molecular mechanisms mediating resistance or sensitivity to treatment. Cytidine deaminase (CDA) was reported to be downregulated in cells derived from patients with Bloom syndrome, a genetic disease associated with a stro...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Mameri, Hamza, Bièche, Ivan, Meseure, Didier, Marangoni, Elisabetta, Buhagiar-Labarchéde, Géraldine, Nicolas, André, Vacher, Sophie, Onclercq-Delic, Rosine, Rajapakse, Vinodh, Varma, Sudhir, Reinhold, William C., Pommier, Yves, Amor-Guéret, Mounira
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430158/
https://ncbi.nlm.nih.gov/pubmed/27601591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0626
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