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Disease mutations in striated muscle myosins

Over 1000 disease-causing missense mutations have been found in human β-cardiac, α-cardiac, embryonic and adult fast myosin 2a myosin heavy chains. Most of these are found in human β-cardiac myosin heavy chain. Mutations in β-cardiac myosin cause hypertrophic cardiomyopathy predominantly, whereas th...

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Bibliografiske detaljer
Udgivet i:Biophys Rev
Main Authors: Parker, Francine, Peckham, Michelle
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429545/
https://ncbi.nlm.nih.gov/pubmed/32651905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-020-00721-5
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