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6‐Hydroxydopamine lesion and levodopa treatment modify the effect of buspirone in the substantia nigra pars reticulata

BACKGROUND AND PURPOSE: l‐DOPA‐induced dyskinesia (LID) is considered a major complication in the treatment of Parkinson's disease (PD). Buspirone (5‐HT(1A) partial agonist) have shown promising results in the treatment of PD and LID, however no 5‐HT‐based treatment has been approved in PD. The...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Vegas‐Suárez, Sergio, Pisanò, Clarissa Anna, Requejo, Catalina, Bengoetxea, Harkaitz, Lafuente, Jose Vicente, Morari, Michele, Miguelez, Cristina, Ugedo, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429490/
https://ncbi.nlm.nih.gov/pubmed/32464686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15145
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