Embryonic exposures to mono-2-ethylhexyl phthalate (MEHP) induce larval steatosis in zebrafish independent of Nrf2a signaling

Mono-2-ethylhexyl phthalate (MEHP) is the primary metabolite of the ubiquitous plasticizer and toxicant, di-2-ethylhexyl phthalate (DEHP). MEHP exposure has been linked to abnormal development, increased oxidative stress, and metabolic syndrome in vertebrates. Nuclear Factor, Erythroid 2 Like 2 (Nrf...

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Udgivet i:J Dev Orig Health Dis
Main Authors: Sant, Karilyn E., Moreau, Hadley M., Williams, Larissa M., Jacobs, Haydee M., Bowsher, Anna Marie, Boisvert, Jason D., Smolowitz, Roxanna M., Pantazis, Jacob, Annunziato, Kate, Nguyen, Malina, Timme-Laragy, Alicia
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429360/
https://ncbi.nlm.nih.gov/pubmed/32063256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S2040174420000057
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