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Burkitt lymphoma: bridging the gap between advances in molecular biology and therapy
Genomic studies have revealed molecular mechanisms involved in the pathogenesis of Burkitt’s lymphoma, including the ID3/TCF3-dependent centroblast gene expression program, tonic PI3K-AKT-mTOR signaling, and deregulation of cell cycle and apoptosis through mutations in cyclin D3, CDKN2A, or TP53. Un...
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| Publié dans: | Leuk Lymphoma |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429355/ https://ncbi.nlm.nih.gov/pubmed/32255708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2020.1747068 |
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