High-fat diet and antibiotics cooperatively impair mitochondrial bioenergetics to trigger dysbiosis that exacerbates pre-Inflammatory Bowel Disease

The clinical spectra of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) intersect to form a scantily defined overlap syndrome, termed pre-IBD. We show that increased Enterobacteriaceae and reduced Clostridia abundance distinguish the fecal microbiota of pre-IBD patients from IBS...

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Gepubliceerd in:Cell Host Microbe
Hoofdauteurs: Lee, Jee-Yon, Cevallos, Stephanie A., Byndloss, Mariana X., Tiffany, Connor R., Olsan, Erin E., Butler, Brian P., Young, Briana M., Rogers, Andrew W.L., Nguyen, Henry, Kim, Kyongchol, Choi, Sang-Woon, Bae, Eunsoo, Lee, Je Hee, Min, Ui-Gi, Lee, Duk-Chul, Bäumler, Andreas J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429289/
https://ncbi.nlm.nih.gov/pubmed/32668218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.06.001
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