Gestational hypoxia inhibits pregnancy-induced upregulation of Ca(2+) sparks and spontaneous transient outward currents in uterine arteries via heightened endoplasmic reticulum/oxidative stress

Hypoxia during pregnancy profoundly affects uterine vascular adaptation and increases the risk of pregnancy complications including preeclampsia and fetal intrauterine growth restriction. We recently demonstrated that increases in Ca(2+) sparks and spontaneous transient outward currents (STOCs) play...

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Publicado no:Hypertension
Main Authors: Hu, Xiang-Qun, Song, Rui, Romero, Monica, Dasgupta, Chiranjib, Min, Joseph, Hatcher, Daisy, Xiao, Daliao, Blood, Arlin, Wilson, Sean M., Zhang, Lubo, Longo, Lawrence D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429261/
https://ncbi.nlm.nih.gov/pubmed/32683903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15235
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