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Beyond Glycolysis: Hypoxia Signaling as a Master Regulator of Alternative Metabolic Pathways and the Implications in Clear Cell Renal Cell Carcinoma

The relationship between kidney cancer, specifically clear cell renal cell carcinoma (ccRCC), and the hypoxia signaling program has been extensively characterized. Its underlying role as the primary driver of the disease has led to the development of the most effective targeted therapies to date. Ce...

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Publicado en:Cancer Lett
Main Authors: Bacigalupa, Zachary A., Rathmell, W. Kimryn
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429250/
https://ncbi.nlm.nih.gov/pubmed/32512023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.05.034
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