Transcription and DNA Methylation Patterns of Blood-Derived CD8(+) T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis

BACKGROUND & AIMS: Gene expression patterns of CD8(+) T cells have been reported to correlate with clinical outcomes of adults with inflammatory bowel diseases (IBD). We aimed to validate these findings in independent patient cohorts. METHODS: We obtained peripheral blood samples from 112 childr...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Gasparetto, Marco, Payne, Felicity, Nayak, Komal, Kraiczy, Judith, Glemas, Claire, Philip-McKenzie, Yosef, Ross, Alexander, Edgar, Rachel D., Zerbino, Daniel R., Salvestrini, Camilla, Torrente, Franco, Ventham, Nicholas T., Kalla, Rahul, Satsangi, Jack, Sarkies, Peter, Heuschkel, Robert, Zilbauer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: by the AGA Institute 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428744/
https://ncbi.nlm.nih.gov/pubmed/32814113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.08.017
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