Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia

BACKGROUND: Renal artery stenosis is a common cause of renal ischemia, contributing to the development of chronic kidney disease. To investigate the role of local CD40 expression in renal artery stenosis, Goldblatt 2‐kidney 1‐clip surgery was performed on hypertensive Dahl salt‐sensitive rats (S rat...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Zhang, Shungang, Breidenbach, Joshua D., Khalaf, Fatimah K., Dube, Prabhatchandra R., Mohammed, Chrysan J., Lad, Apurva, Stepkowski, Stanislaw, Hinds, Terry D., Kumarasamy, Sivarajan, Kleinhenz, Andrew, Tian, Jiang, Malhotra, Deepak, Kennedy, David J., Cooper, Christopher J., Haller, Steven T.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428653/
https://ncbi.nlm.nih.gov/pubmed/32200719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014072
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