Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia

BACKGROUND: Renal artery stenosis is a common cause of renal ischemia, contributing to the development of chronic kidney disease. To investigate the role of local CD40 expression in renal artery stenosis, Goldblatt 2‐kidney 1‐clip surgery was performed on hypertensive Dahl salt‐sensitive rats (S rat...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Zhang, Shungang, Breidenbach, Joshua D., Khalaf, Fatimah K., Dube, Prabhatchandra R., Mohammed, Chrysan J., Lad, Apurva, Stepkowski, Stanislaw, Hinds, Terry D., Kumarasamy, Sivarajan, Kleinhenz, Andrew, Tian, Jiang, Malhotra, Deepak, Kennedy, David J., Cooper, Christopher J., Haller, Steven T.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428653/
https://ncbi.nlm.nih.gov/pubmed/32200719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014072
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