Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia

BACKGROUND: Renal artery stenosis is a common cause of renal ischemia, contributing to the development of chronic kidney disease. To investigate the role of local CD40 expression in renal artery stenosis, Goldblatt 2‐kidney 1‐clip surgery was performed on hypertensive Dahl salt‐sensitive rats (S rat...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Zhang, Shungang, Breidenbach, Joshua D., Khalaf, Fatimah K., Dube, Prabhatchandra R., Mohammed, Chrysan J., Lad, Apurva, Stepkowski, Stanislaw, Hinds, Terry D., Kumarasamy, Sivarajan, Kleinhenz, Andrew, Tian, Jiang, Malhotra, Deepak, Kennedy, David J., Cooper, Christopher J., Haller, Steven T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428653/
https://ncbi.nlm.nih.gov/pubmed/32200719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014072
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