PCSK9 Protein and rs562556 Polymorphism Are Associated With Arterial Plaques in Healthy Middle‐Aged Population: The STANISLAS Cohort

BACKGROUND: PCSK9 (Proprotein convertase subtilisin/kexin type 9) binds low‐density lipoprotein receptor, preventing its recycling. PCSK9 is a risk predictor and a biotarget in atherosclerosis. The PCSK9‐rs562556 variant has been reported as a gain‐of‐function mutation. The aim of this study was to...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Ferreira, João Pedro, Xhaard, Constance, Lamiral, Zohra, Borges‐Canha, Marta, Neves, João Sérgio, Dandine‐Roulland, Claire, LeFloch, Edith, Deleuze, Jean‐François, Bacq‐Daian, Delphine, Bozec, Erwan, Girerd, Nicolas, Boivin, Jean‐Marc, Zannad, Faiez, Rossignol, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428603/
https://ncbi.nlm.nih.gov/pubmed/32208829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014758
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