PCSK9 Protein and rs562556 Polymorphism Are Associated With Arterial Plaques in Healthy Middle‐Aged Population: The STANISLAS Cohort

BACKGROUND: PCSK9 (Proprotein convertase subtilisin/kexin type 9) binds low‐density lipoprotein receptor, preventing its recycling. PCSK9 is a risk predictor and a biotarget in atherosclerosis. The PCSK9‐rs562556 variant has been reported as a gain‐of‐function mutation. The aim of this study was to...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Ferreira, João Pedro, Xhaard, Constance, Lamiral, Zohra, Borges‐Canha, Marta, Neves, João Sérgio, Dandine‐Roulland, Claire, LeFloch, Edith, Deleuze, Jean‐François, Bacq‐Daian, Delphine, Bozec, Erwan, Girerd, Nicolas, Boivin, Jean‐Marc, Zannad, Faiez, Rossignol, Patrick
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428603/
https://ncbi.nlm.nih.gov/pubmed/32208829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014758
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires