Self-targeting, zwitterionic micellar dispersants enhance antibiotic killing of infectious biofilms—An intravital imaging study in mice

Extracellular polymeric substances (EPS) hold infectious biofilms together and limit antimicrobial penetration and clinical infection control. Here, we present zwitterionic micelles as a previously unexplored, synthetic self-targeting dispersant. First, a pH-responsive poly(ε-caprolactone)-block-pol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Tian, Shuang, Su, Linzhu, Liu, Yong, Cao, Jingjing, Yang, Guang, Ren, Yijin, Huang, Fan, Liu, Jianfeng, An, Yingli, van der Mei, Henny C., Busscher, Henk J., Shi, Linqi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2020
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428326/
https://ncbi.nlm.nih.gov/pubmed/32851173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb1112
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