Indirubin inhibits Wnt/β-catenin signal pathway via promoter demethylation of WIF-1

BACKGROUND: Psoriasis is a common inflammatory skin disease. Abnormal proliferation of keratinocytes is one of the psoriatic histopathological features. Indirubin has an essential effect on the proliferation and activation of keratinocytes; however, in psoriasis, the specific mechanism of action of...

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Bibliographic Details
Published in:BMC Complement Med Ther
Main Authors: Liu, Shou Gang, Luo, Guang Pu, Qu, Yong Bin, Chen, Yong Feng
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427955/
https://ncbi.nlm.nih.gov/pubmed/32795328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-03045-9
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