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N-acetyl-D-glucosamine kinase binds dynein light chain roadblock 1 and promotes protein aggregate clearance

Emerging evidence indicates that neurodegenerative diseases (NDs) result from a failure to clear toxic protein aggregates rather than from their generation. We previously showed N-acetylglucosamine kinase (NAGK) promotes dynein functionality and suggested this might promote aggregate removal and eff...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ripon, Md. Kamal Hossain, Lee, HyunSook, Dash, Raju, Choi, Ho Jin, Oktaviani, Diyah Fatimah, Moon, Il Soo, Haque, Md. Nazmul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427805/
https://ncbi.nlm.nih.gov/pubmed/32796833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02862-7
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