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A novel approach to genetic engineering of T-cell subsets by hematopoietic stem cell infection with a bicistronic lentivirus

Lentiviral modification of hematopoietic stem cells (HSCs) paved the way for in vivo experimentation and therapeutic approaches in patients with genetic disease. A disadvantage of this method is the use of a ubiquitous promoter leads not only to genetic modification of the leukocyte subset of intere...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Bogert, N. V., Furkel, J., Din, S., Braren, I., Eckstein, V., Müller, J. A., Uhlmann, L., Katus, H. A., Konstandin, M. H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426960/
https://ncbi.nlm.nih.gov/pubmed/32792615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70793-6
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