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Coupling Coarse-Grained to Fine-Grained Models via Hamiltonian Replica Exchange

[Image: see text] The energy landscape of biomolecular systems contains many local minima that are separated by high energy barriers. Sampling this landscape in molecular dynamics simulations is a challenging task and often requires the use of enhanced sampling techniques. Here, we increase the samp...

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Bibliografski detalji
Izdano u:J Chem Theory Comput
Glavni autori: Liu, Yang, Pezeshkian, Weria, Barnoud, Jonathan, de Vries, Alex H., Marrink, Siewert J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426904/
https://ncbi.nlm.nih.gov/pubmed/32569465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c00429
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