Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy

Both iron metabolism and mitophagy, a selective mitochondrial degradation process via autolysosomal pathway, are fundamental for the cellular well-being. Mitochondria are the major site for iron metabolism, especially the biogenesis of iron-sulfur clusters (ISCs) via the mitochondria-localized ISCs...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Wu, Hao, Wei, Huifang, Zhang, Di, Sehgal, Sheikh Arslan, Zhang, Dejiu, Wang, Xiaohui, Qin, Yan, Liu, Lei, Chen, Quan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426581/
https://ncbi.nlm.nih.gov/pubmed/32795936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101661
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