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Identification of modified peptides using localization-aware open search

Identification of post-translationally or chemically modified peptides in mass spectrometry-based proteomics experiments is a crucial yet challenging task. We have recently introduced a fragment ion indexing method and the MSFragger search engine to empower an open search strategy for comprehensive...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Yu, Fengchao, Teo, Guo Ci, Kong, Andy T., Haynes, Sarah E., Avtonomov, Dmitry M., Geiszler, Daniel J., Nesvizhskii, Alexey I.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426425/
https://ncbi.nlm.nih.gov/pubmed/32792501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17921-y
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