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Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer

Metastasis is the leading cause of cancer-related death. This multistage process involves contribution from both tumour cells and the tumour stroma to release metastatic cells into the circulation. Circulating tumour cells (CTCs) survive circulatory cytotoxicity, extravasate and colonise secondary s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Green, Darrell, Eyre, Heather, Singh, Archana, Taylor, Jessica T., Chu, Jason, Jeys, Lee, Sumathi, Vaiyapuri, Coonar, Aman, Rassl, Doris, Babur, Muhammad, Forster, Duncan, Alzabin, Saba, Ponthan, Frida, McMahon, Adam, Bigger, Brian, Reekie, Tristan, Kassiou, Michael, Williams, Kaye, Dalmay, Tamas, Fraser, William D., Finegan, Katherine G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426263/
https://ncbi.nlm.nih.gov/pubmed/32655131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1379-0
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