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Degradation of Serrate via ubiquitin-independent 20S proteasome to survey RNA metabolism
Serrate (SE) is a key factor in RNA metabolism. Here, we report that SE binds 20S core proteasome α subunit G1 (PAG1) among other components and is accumulated in their mutants. Purified PAG1-containing 20S proteasome degrades recombinant SE via an ATP- and ubiquitin-independent manner in vitro. Not...
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| Τόπος έκδοσης: | Nat Plants |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7426255/ https://ncbi.nlm.nih.gov/pubmed/32690892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41477-020-0721-4 |
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