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Proteomic analysis of protein turnover by metabolic whole rodent pulse-chase isotopic labeling and shotgun mass spectrometry analysis

The analysis of protein half-life and degradation dynamics has proven critically important to our understanding of a broad and diverse set of biological conditions ranging from cancer to neurodegeneration. Historically these protein turn over measures have been performed in cells by monitoring prote...

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Bibliografische gegevens
Gepubliceerd in:Methods Mol Biol
Hoofdauteurs: Savas, Jeffrey N., Park, Sung Kyu, Yates, John R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426012/
https://ncbi.nlm.nih.gov/pubmed/26867752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3524-6_18
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