Different types of cartilage neotissue fabricated from collagen hydrogels and mesenchymal stromal cells via SOX9, TGFB1 or BMP2 gene transfer

OBJECTIVE: As native cartilage consists of different phenotypical zones, this study aims to fabricate different types of neocartilage constructs from collagen hydrogels and human mesenchymal stromal cells (MSCs) genetically modified to express different chondrogenic factors. DESIGN: Human MSCs deriv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Weißenberger, Manuel, Weißenberger, Manuela H., Wagenbrenner, Mike, Heinz, Tizian, Reboredo, Jenny, Holzapfel, Boris M., Rudert, Maximilian, Groll, Jürgen, Evans, Christopher H., Steinert, Andre F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425924/
https://ncbi.nlm.nih.gov/pubmed/32790806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237479
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