Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions

Alpha-synucleinopathies are a group of progressive neurodegenerative disorders, characterized by intracellular deposits of aggregated α-synuclein (αS). The clinical heterogeneity of these diseases is thought to be attributed to conformers (or strains) of αS but the contribution of inclusions in vari...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Tanriöver, Gaye, Bacioglu, Mehtap, Schweighauser, Manuel, Mahler, Jasmin, Wegenast-Braun, Bettina M., Skodras, Angelos, Obermüller, Ulrike, Barth, Melanie, Kronenberg-Versteeg, Deborah, Nilsson, K. Peter R., Shimshek, Derya R., Kahle, Philipp J., Eisele, Yvonne S., Jucker, Mathias
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425556/
https://ncbi.nlm.nih.gov/pubmed/32787922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00993-8
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