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Circular RNA hsa_circ_0000073 contributes to osteosarcoma cell proliferation, migration, invasion and methotrexate resistance by sponging miR-145-5p and miR-151-3p and upregulating NRAS

An increasing number of studies have demonstrated that circular RNAs (circRNAs), as promising therapeutic targets, are essential for diverse human diseases, especially cancer. However, the potential functions and complex mechanisms of most circRNAs in osteosarcoma (OS) are still not fully elucidated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Li, Xia, Liu, Yi, Zhang, Xiangxin, Shen, Jun, Xu, Renjie, Liu, Yubo, Yu, Xiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425447/
https://ncbi.nlm.nih.gov/pubmed/32706759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103423
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