MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes

Homologous apolipoproteins of MICOS complex, MIC26 and MIC27, show an antagonistic regulation of their protein levels, making it difficult to deduce their individual functions using a single gene deletion. We obtained single and double knockout (DKO) human cells of MIC26 and MIC27 and found that DKO...

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Bibliografiske detaljer
Udgivet i:Life Sci Alliance
Main Authors: Anand, Ruchika, Kondadi, Arun Kumar, Meisterknecht, Jana, Golombek, Mathias, Nortmann, Oliver, Riedel, Julia, Peifer-Weiß, Leon, Brocke-Ahmadinejad, Nahal, Schlütermann, David, Stork, Björn, Eichmann, Thomas O, Wittig, Ilka, Reichert, Andreas S
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425215/
https://ncbi.nlm.nih.gov/pubmed/32788226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000711
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