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Dapagliflozin Activates Neurons in the Central Nervous System and Regulates Cardiovascular Activity by Inhibiting SGLT-2 in Mice

PURPOSE: This study investigates the possible effect and central mechanism of novel antidiabetic medication sodium glucose transporter-2 (SGLT-2i) on the cardiovascular activity. MATERIAL AND METHODS: Thirty-four normal male C57BL/6 mice were randomly assigned to 2 groups to receive single Dapaglifl...

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Detalhes bibliográficos
Publicado no:Diabetes Metab Syndr Obes
Main Authors: Nguyen, Thiquynhnga, Wen, Song, Gong, Min, Yuan, Xinlu, Xu, Dongxiang, Wang, Chaoxun, Jin, Jianlan, Zhou, Ligang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425107/
https://ncbi.nlm.nih.gov/pubmed/32848437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S258593
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