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New Strategies for Forward Genetic Screening and Single Cell Analysis with CRISPRi Transcriptional Repressors
The power of CRISPR-Cas9 for genome engineering has continued to grow in recent years. The ability to perform large-scale, whole genome loss-of-function screens has allowed for new breakthroughs identifying gene pathways in drug resistance and disease. CRISPRi (inhibition) allows for targeted suppre...
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| Publicado no: | J Biomol Tech |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7425014/ |
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